Harlequins are back in action this weekend hoping to end a run of four straight away defeats as they take on Gloucester. 

Quins have been strong at home in recent weeks, but their last away win in any competition was against Bath on 2nd December. 

Their opponents in Gloucester come into this game on the back of a bad run, having won just twice in their last seven across all competitions. 

Kick-off at the Kingsholm Stadium is at 7:45pm on Friday. 

London Scottish will be up against it to make the Championship Cup knock-out rounds as they are on the road against Doncaster Knights. 

Last weekend's defeat against Bedford Blues sees Scottish four point adrift at the bottom of Pool B and they will more than likely need to be one of the best third-placed teams to make the latter stages of the competition. 

Doncaster are their opposition this weekend, sitting top of Pool B, but they were on the wrong end of a crushing defeat against Coventry last time out, 42-12. 

Kick-off at Castle Park is at 2:30pm on Saturday. 

Ealing Trailfinders will need a win against Nottingham to reaffirm their place atop Pool A in the Championship Cup. 

A defeat by the narrowest of margins against Jersey Reds last week means the Trailfinders rocky start to 2023 continued and they now only hold a one-point advantage over their Channel Islands adversaries. 

Nottingham are already in a fight to be one of the two best third-placed teams in order to progress to the next phase, and with away trips against the leagues two top clubs to come, that will be a tall order. 

Kick-off at Trailfinders Sports Club is at 3pm on Saturday. 

London Welsh are back in action looking to use their resounding win from two weeks ago as motivation when they face Camberley. 

Welsh were not in action last weekend, but they have won their last two in resounding fashion, 51-15 against Banbury and 42-27 against Sutton and Epsom. 

Camberley were in fine try-scoring form themselves last weekend, winning 50-26 against Sutton and Epsom and have only lost twice all season as they attempt to hunt down Wimbledon at the top of Regional One South Central. 

Kick-off at Watchetts Recreation Ground is at 2pm on Saturday. 

Teddington RFC will hope to follow up one of their best performances of the season last weekend when they face Old Amplefordians. 

The Antlers defeated Purley John Fisher 53-6 to maintain their perfect record and have now scored over 400 points in 15 games this season. 

Their opponents this weekend in Old Amplefordians are in indifferent form, but have recorded some big wins recently, winning three of seven since playing Teddington, but in those three games scoring a combined 135 points. 

Kick-off at Bushy Park is at 2:30pm on Saturday. 

Elsewhere in the area, London Irish host Northampton in the Premiership Cup, Richmond are at home against Ampthill on Friday night, Chobham visit Twickenham RFC, and Kingston RFC are also at home against Old Walcountians.